Pseudomonas Exotoxin-mediated Selection Yields Cells with Altered Expression of Low-Density Lipoprotein Receptor-related Protein
نویسندگان
چکیده
David J. FitzGerald,* Charlotte M. Fryling,* Alexey Zdanovsky,* Catharine B. Saelinger,* Maria Kounnas, ~ Jeffrey A. Winkles, § Dudley Strickland, ~ and Stephen Lepplall *Laboratory of Molecular Biology, National Cancer Institute, Division of Cancer Biology, Diagnosis and Centers, National Institutes of Health, Bethesda, Maryland 20892; *Department of Molecular Genetics, University of Cincinnati, Cincinnati, Ohio 45267; ~Holland Laboratory, American Red Cross, Rockville, Maryland 20855; and IDental Institute, National Institutes of Health, Bethesda, Maryland 20892
منابع مشابه
Pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein [published erratum appears in J Cell Biol 1995 Aug;130(4):1015]
The alpha 2-macroglobulin (alpha 2M) receptor/low-density lipoprotein receptor-related protein (LRP) is important for the clearance of proteases, protease-inhibitor complexes, and various ligands associated with lipid metabolism. While the regulation of receptor function is poorly understood, the addition of high concentrations of the 39-kD receptor-associated protein (RAP) to cells inhibits th...
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تاریخ انتشار 2002